CHO Cells Genetic Engineering
Chinese hamster ovary (CHO) cells are one of the most commonly used mammalian cell lines in the biopharmaceutical industry for the production of therapeutic proteins. CHO cells are preferred over other cell lines due to their ability to correctly fold, assemble, and post-translationally modify proteins, which is essential for their biological activity. Genetic engineering of CHO cells has become an increasingly important area of research, as it has the potential to improve the productivity and quality of therapeutic proteins. Genetic engineering of CHO cells modification involves the manipulation of the cell's genome to achieve a specific outcome, such as increased productivity, improved product quality, or altered post-translational modifications. This is achieved by introducing a foreign DNA sequence into the genome of the CHO cell using various techniques, including transfection, electroporation, or viral vectors. The foreign DNA sequence can encode for a protein of interest, a selection marker, or a regulatory element that can modulate gene expression.
CD Biosynsis is a leading provider of synthetic biology services. We will highlight our services for genetic engineering of CHO Cells Genetic Engineering, and how we can help our clients achieve their goals in the development of biologics.